Jump to Topic:

• Clinical Guidance and Recommendations
• JYNNEOS (Smallpox/mpox) Vaccine Information
• Intradermal Vaccination Resources
• Other Vaccine Administration Resources
• Vaccine Management and Reporting
• Vaccine and Adverse Reactions Information
• Mpox Disease Information and Educational Resources
• Other Resources

Clinical Guidance and Recommendations

• CDPH JYNNEOS mpox vaccine, administration and dosing
• CDPH mpox FAQs for Providers & LHDs
• CDC mpox and Smallpox Vaccine Guidance
• Interim Clinical Considerations for Use of JYNNEOS and ACAM2000 Vaccines during the 2022 U.S. mpox Outbreak (CDC)
• CDPH mpox Vaccine Page
• CDPH mpox Vaccine Prioritization Guidance
• CDPH Considerations for Expanded mpox Post-Exposure Prophylaxis (PEP++)
• MMWR: Use of JYNNEOS for Pre-exposure Vaccination of Persons at Risk for Occupational Exposure to Orthopoxviruses: Recommendations of the Advisory Committee on Immunization Practices, U.S., 2022 
• MMWR: Interim Guidance for Prevention and Treatment of mpox in Persons with HIV Infection — United States, August 2022

JYNNEOS (Smallpox/Mpox) Vaccine Information

JYNNEOS is FDA-approved for use in adults 18 years and older as a two-dose series, administered subcutaneously. On 8/9/22, FDA granted Emergency Use Authorization as a two-dose series for the following uses:

· Use in children under 18 years of age, administered subcutaneously

· Use in adults 18 years and older, administered intradermally.

• JYNNEOS Vaccine Fact Sheet | Provider Letter
• Screening Checklist for JYNNEOS Mpox Vaccination | Spanish
• Mpox Vaccination Registration & Consent Form (adults/minors) | Spanish
• JYNNEOS Vaccine Information Statement (VIS)  |  Spanish (distribute to recipient prior to vaccination)
• JYNNEOS Package Insert (6/2021)
• JYNNEOS EUA Fact Sheet for Providers (8/2022)
• JYNNEOS EUA Fact Sheet for Recipients and Caregivers (8/2022)

   

Intradermal Vaccination Resources

• JYNNEOS Intradermal Administration job aid (CDC)
• JYNNEOS Intradermal Administration video (CDC)
• JYNNEOS Preparation and Administration Summary for Intradermal Administration (CDC)
• JYNNEOS Standing Orders for Intradermal Administration (CDC)
• JYNNEOS Intradermal Vaccination: Patient Counseling (CDC)
• JYNNEOS Intradermal Vaccination Considerations for Specific Populations (CDC)
• JYNNEOS EUA Fact Sheet for Providers (8/2022)
• JYNNEOS EUA Fact Sheet for Recipients and Caregivers (8/2022)
• CDC/FDA COCA Call: Interim Clinical Considerations for Mpox Vaccination (slides, 8/2022)
• JYNNEOS Intradermal Administration Guidance (CDPH)

Other Vaccine Administration Resources

• JYNNEOS Preparation and Administration Summary for Subcutaneous Administration
• Subcutaneous Injection video (CDC)
• Injectable Vaccines by Route
• Preparing Liquid Vaccines
• Administering Injections

   

Vaccine Management and Reporting

• Mpox Requirements at a Glance (NEW!)
• JYNNEOS Storage & Handling Summary (CDC)
• Instructions for Flipping Off Cap for MVA-BN
• General Vaccine Storage and Handling job aids
• California Immunization Record:
  Blank for Computer Print Out |  Vaccines Listed to Fill Out by Hand
• JYNNEOS Standing Orders for Subcutaneous Administration (CDC)
• JYNNEOS Standing Orders for Intradermal Administration (CDC)
• JYNNEOS Standing Orders template (Word) (CDPH, LA, SF)

   

Vaccine and Adverse Reactions Information

• JYNNEOS Vaccine Administration Errors and Deviations (CDC)
• JYNNEOS Contraindications & Precautions (CDC)
• List of Adverse Events after JYNNEOS Vaccination Requiring VAERS Reporting (CDC)
• Vaccine Adverse Event Reporting System (VAERS)
• Office Management of Anaphylaxis (CDPH)
• VAERS and VERP flyer (CDPH)

   

Mpox Disease Information and Educational Resources

• California Primary Care Association (CPCA) Mpox Webinar, 8/23/22 Slides and Recording
• Mpox webpage (CDPH)
• Mpox Q&A (CDPH)
• Mpox Communications Toolkit (CDPH)
• US Mpox Outbreak 2022: Situational Summary (CDC)
• Mpox CBO Partner Letter (HHS)
• Mpox Information for Healthcare Professionals (CDC)
• Interim Clinical Guidance for Treatment of Mpox (CDC)
• Mpox Clinician FAQs (CDC)

Other Resources

• Coming Soon: Mpox Vaccines as Medi-Cal Benefits
• Mpox Services and Reimbursement for FQHC, RHC, IHS-MOA and Tribal FQHC Providers
• Orthopoxvirus and Mpox Coding & Guidance (AMA)
• HRSA Countermeasures Injury Compensation Program (CISP)
• Current Therapeutic Guidance on Mpox (IHS)